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Aims of Study:
Nocturia, from
which patients feel the most uncomfortable, is one of the frequently complained
urologic symptoms combined with insomnia. Neither incidence nor classification
of nocturia exists yet. In this study we analyzed the history, micturition diary,
urodynamic study and investigated the etiology of nocturia and then classified
them.
Materials and Methods:
From January 1998 to September 1999, 152 patients underwent urodynamic study(UDS)
and completed three days micturition diary, and we studied them retrospectively.
We defined nocturia as more two times voiding during sleep, nocturnal polyuria
as nocurnal urine volume is more than 35% of 24hours urine volume, nocturnal
detrusor overactivity as diminishing nocturnal bladder capacity. We classified
the etiology of nocturia into four groups : Pure nocturnal polyuria, Pure nocturnal
detrusor overactivity, Mixed, and others based on the micturition diaries and
the results of UDS. Polyuria(24hours urine output > 2500cc) was classified separately.
Results: Of the 152 cases, 66 were men and 86 were women with mean age 62.9years
(27-88) and 52.3years(26- 81) respectively. The mean number of nocturia was
3.3(3.4 for men, 3.1 for women). Pure nocturnal polyuria, nocturnal detrusor
overactivity and mixed were 41.4%, 17.8% and 25.7% respectively. Nocturnal polyuria
had no relations to detrusor overactivity, bladder outlet obstruction and impaired
detrusor contractility, but increased along with age(p=0.001) and in men(p=0.047).
Seventeen(11.2%) had polyuria.
|
|
Total |
Male |
Female |
No. of nocturia |
|
Pure
NP Pure
NDO Mixed(NP+NDO) Others |
63(41.4%) 27(17.8%) 39(25.7%)
23(15.1%)
|
29(43.9%) 9(13.6%) 21(31.8%) 7(10.6%)
|
34(39.5%) 18(20.9%) 18(20.9%) 16(18.6%)
|
3.1 3.4 3.7 3.0 |
|
Polyuria1 |
7(11.2%)
|
9(13.6%)
|
2(2.3%)
|
3.5 |
(NP: nocturnal polyuria, NDO: nocturnal detrusor overactivity)
Conclusion:
In 84.9% of nocturia patients there were nocturnal polyuria or nocturnal
detrusor overactivity and 11.2% of them there were polyuria. Therefore we can
concluded that these three causes were the main etiology of nocturia and nocturia
could be classified and treated based on these results.