|

|
CLINICAL SIGNIFICANCE
OF DETRUSOR SPHINCTER DYSSYNERGIA TYPE IN POST TRAUMATIC SPINAL
CORD INJURY PATIENTS
|
|
| |
|
|
|
|
|
|
|
|
| |
|

|
Authors:
|

|
R.R. Dmochowski and
K.J. Weld
|
|
| |
|
|
|
|
|
|
|
|
| |
|
|

|
Institution:
|

|
University of Tennessee,
Memphis, Tennessee, USA
|
|
| |
|
|
|
|
|
|
|
|
| |
|
|
|
| |
|
|
|
|
|
|
|
|
| |
|
|
|
|
| |
|
|
|
|
|
|
|
|
| |
|
|
|
|
|
| |
|
|
|
|
|
|
|
|
Aims of Study:
This study investigated the clinical significance of detrusor sphincter dyssynergia
(DSD) type. Specifically, the associations of DSD type with level of injury,
completeness of injury, age of injury, upper tract complications, and renal
function were evaluated.
Methods:
A retrospective review of the charts, video-urodynamic studies and upper tract
radiographic studies of 269 patients with post-traumatic suprasacral spinal
cord injuries (SCI) was performed. The patients were categorized according to
DSD type, level of injury, completeness of injury, age of injury, and upper
tract complications.
Results:
Of the 269 patients 20 (7.4%), 112 (41.6%), 104 (38.7%) and 33 (12.3%) had no
DSD, type 1, type 2 and type 3 DSD, respectively. No significant association
between specific level of injury (cervical, thoracic, and lumbar) and DSD type
was found (p=0.64). The association of completeness of injury to DSD type was
significant (p<0.01). Within the complete injury group, no patients had type
1 DSD, 5 (13.9%) had type 2 DSD, and 31 (86.1%) patients had type 3 DSD. The
incomplete injury group consisted of 112 (48.1%), 99 (42.5%) and 2 (0.9%) patients
with type 1, type 2 and type 3 DSD, respectively. In comparisons to patients
with no DSD, the percentage of patients with type 1 DSD was decreased in older
age of injury cohorts (p=.01), the percentage of patients with type 2 DSD increased
(p=0.04), and the percentage of type 3 DSD remained unchanged (p=.17). Type
3 DSD was strongly associated with each upper tract complication studied. Patients
with type 2 DSD had a significantly greater incidence of upper tract abnormalities,
upper tract stones and elevated serum creatinine relative to patients with no
DSD or type 1 DSD.
Conclusions:
The clinical significance of DSD type was proven by the association of complete
SCI and upper tract complication with type 3 DSD. Patients with incomplete SCI
may convert from type 1 to type 2 DSD over a long term and risk increased susceptibility
to urologic complications.