ICS 1999, Denver
Read by title abstracts
Pelvic floor
PREVALENCE OF GENITAL ORGAN PROLAPSE IN WOMEN WITH INTERSTITIAL CYSTITIS

TL Griebling, TE Takle, KJ Kreder
The unimversity of Iowa, Iowa City, Iowa, U.S.A.

Aims of study The impact of pelvic floor anatomy in interstitial cystitis (IC) patients has not been well documented. It has been hypothesized that irritative coiding symptoms in IC patients may be exacerbated by increased pelvic floor muscle tonicity. This case control study was designed to compare the prevalence of genital organ prolapse in women with and wihtout IC.

Methods Clinical records for 83 women with a confirmed diagnosis of IC evaluated during the past 6 years were reviewed. An age-matched control group of 166 women evaluated for non-enurogenic voiding dysfunction during the same time period was used for comparison. Demographic and clinical data obtained for each patient included age; past medical, surgical, and gynecological history; and pelvic examination results. Genital organ prolapse including cystocele, rectocele, and urethral hypermobility was categorized according to a 4 point scale (0 to 3+). Intergroup differences for each clinical parameter were compared using Chi-square analysis or Fisher`s exact test as appropriate.

Restults The median age in both groups was 49 (range 21-83). Thirty-nine percent of subjects in both groups had undergone prior hysterectomy. The prevalence of urethral hypermobility was significantly lower in IC patients compared to controls ( q > 0.0001). although not statistically significant, the prevalence of both cystocele and rectocele were lowere in IC patients.

Prolapse cystocele rectocele hypermobility

Degree IC% Control % IC % Control % IC % Control%

None (0)

73 60

83 69

71 36

Mild (1+)

16 29

14 25

22 50

Moderate (2+)

8 9

2 4

7 13

Severe (3+)

2 2

0 2

0 1